Lou Gehrig's Disease or ALS is a genetic disease that causes systemic failure of neural functions. A victim of this condition slowly loses control of his or her body and eventually dies. Its primary symptom are shivering tremors.
Archives in the Novus fallout bunker revealed that Tamara Johansen has this disease, as her alternate counterpart died of it. Yaozu claimed that the People of Novus found a cure for it, but this knowledge was lost after the destruction of Novus. The Destiny expedition started searching the Destiny database for cure, but have yet to find it.
Tamara Johansen's disease momentum was halted for a time when she was placed in the stasis pod between 2010 and 2013. After she woke up so would 2018 she feel the first symptoms of the disease. (SGU: "Gauntlet")